Marvin,
Yes, directly with WINE.
Windiz programs, Windiz operating systems from MSDOS to Vista & other OSs can run in Linux. Wine, VirtualBox, CrossOver are 3 ways to run Windiz programs & Mac programs on Linux.
www.winehq.org/
ww.codeweavers.com/products/download_trial_linux/
http://www.virtualbox.org/wiki/End-user_documentation
Wine lets Windiz applications run on Linux directly but safely. CrossOver is a commercial extension of WINE.
Virtual box seems to have windiz built in (got to read more of it) and runs Windiz programs plus others.
VM ware runs on Linux as a host for many other operating systems. When Windiz runs on VM ware, Windiz does not know it is in a virtual machine, does not know it is just another program running.
I am slowly looking for a web describing how some person has made a good GPS mapping software run in VirtualBox but 2 things may happen. 1, I may buy VM Ware, load XP in it & load CoPilot 10 in XP. 2, I may get enough interest to learn how to make VB work for CoPilot 10.
Any one already done it?