Hi jnbedford,
Welcome to Laptop GPS World.
The answer is NO and YES.
Microsoft Streets and Trips 2010 (and earlier versions) doesn't have a feature that automatically creates truck-specific routing, or routing for large vehicles, such as RVs, motorhomes, etc. However, Microsoft streets and Trips still remains a very popular software among RVers and truckers. The reason why this is is rather simple: S&T is an excellent trip planning software. It lets you modify the plotted route easily to fit your needs.
In various user communities you may find people sharing downloadable locations of low bridges, etc.
Here are as couple of links you may find interesting:
POI Mega File - pushpin collections for truckers, RVers, and other travelers