I installed S&T 2010 on Windows 7 64-bit with no problem on my desktop PC. I
did install it from the downloaded trial version and bought the license later after I decided I liked it. Maybe try downloading the trial and install from that, then enter your CD license key.
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NOTE: If you plan on using GPSGate with WIN 7 64-bit, you will need to do the following:
1. After installation copy the file
C:\Program Files (x86)\Franson\GpsGate 2.0\x64\bizVSerialNT.sys
to C:\Windows\System32\Drivers
2. Exit GpsGate (if running)
3. Run GpsGate as Administrator once. (Right click on the GpsGate icon in the Start Menu and select "Run as administrator")
Now the 64-bit driver is installed.
GpsGate for 64-bit Vista and Windows 7