Mapsource 6.16.3 works fine. Surface Pro 1 with the latest release of Win 10 (Threshold_2 Release 10586 Professional). Think of it like Win 10 SP 1.
I dont have 6.13.7 on here yet. If it matters I can try it tomorrow. I have CNNA 2015.4, Metroguide Canada v5, and Backroad Mapbooks BC v4 installed and all seem to work.
nRoute also works. I have been very impressed with Win 10 backward compatibility.