Mobile PC works very well with the Pharos 500 receiver that comes with
Streets&Trips 2008. If the receiver is plugged in when you run Mobile PC it will find it immediately and start using it automatically. You won't have to do anything special to use it.
You can use the Pharos 500 with nroute but you need a program called
GPSGate to convert the data from the Pharos receiver into the proprietary Garmin data protocol. GPSGate is shareware. You can try it free for two weeks then it will stop working unless you pay for it.
...ken...